Extracranial stereotactic radiotherapy as a treatment for oligometastatic prostate cancer: from paliative to curative.

Abstract

Prostate cancer is the most common non-cutaneous neoplasm in men, and when diagnosed at a localized stage, patients present a wide variety of possible therapeutic options, ranging from observation to multimodal treatments that include radiotherapy, radical prostatectomy, and blockade. total androgenic, as the case may be. When the diagnosis is made at stage IV, until a couple of years ago, radiotherapy was used as a palliative treatment, only to relieve pain and prevent pathological fractures in load-bearing bones. Currently, a new concept has been incorporated, that of oligometastatic disease, as an intermediate state between localized and systemic or metastatic disease, in which the treatment of primary cancer and secondary lesions has curative potential. Extracranial stereotactic radiotherapy is a novel treatment modality, with great potential in the management of neoplastic diseases, especially oligometastases, since high doses of radiation can be administered in a rapid, safe, and effective manner, respecting the tolerances of the organs adjacent to our target. The development of a narrative review on extracranial stereotactic radiotherapy as a treatment for oligometastatic prostate cancer allows us to know the technique, fractionations and results, to motivate the development and use of these tools and thus improve the prognosis of this group of patients and disseminate their application in Venezuela