Basal and postprandial triglycerides in relation to remaining cholesterol and insulin resistance

Triglycerides in relation to remaining cholesterol and insulin resistance

Abstract

A fasting triglyceride level <100 mg/dl is associated with a low risk of Cardiovascular Disease (CVD) and predicts postprandial triglycerides less than 150mg/dL. Objective: to assess the increase in postprandial triglycerides based on fasting triglycerides at higher values ​​and less than 100 mg|dL, in patients after their usual breakfast and correlate them with Insulin Resistance measured by HOMA, Cholesterol and its fractions as well as Non-HDL Cholesterol and Remnant Cholesterol. Method: Descriptive, retrospective longitudinal study, with a population of patients from the Endocrinology clinic of the Dr. Carlos Arvelo Military Hospital in Caracas. Samples were taken fasting and 2 hours after a meal, and patients were divided into 2 groups according to triglycerides higher or lower than 100mg/dL. Results: Patients with triglycerides lower than 100mg/dL had lower triglycerides at 2 hours. at 150mg/dl, in both groups triglycerides rose an average of 49mg/dL. Total cholesterol, GGT and SGPT were higher in patients with basal triglycerides greater than 100mg/dL and HDL cholesterol was lower in patients with triglycerides greater than 100mg/dL Conclusions: One of the important findings in our study was to observe that triglycerides below 100mg/dL were associated with high HDL cholesterol above 50mg/dL while triglycerides above 100mg/dL were associated with low HDL cholesterol, increased insulin resistance as measured by HOMA and transaminases.